A novel Axin2 knock‐in mouse model for visualization and lineage tracing of WNT / CTNNB1 responsive cells
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چکیده
منابع مشابه
Lineage tracing with Axin2 reveals distinct developmental and adult populations of Wnt/β-catenin-responsive neural stem cells.
Since the discovery of neural stem cells in the mammalian brain, there has been significant interest in understanding their contribution to tissue homeostasis at both the cellular and molecular level. Wnt/β-catenin signaling is crucial for development of the central nervous system and has been implicated in stem cell maintenance in multiple tissues. Based on this, we hypothesized that the Wnt p...
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ژورنال
عنوان ژورنال: genesis
سال: 2020
ISSN: 1526-954X,1526-968X
DOI: 10.1002/dvg.23387